Herbal Detox program clinical evidence
Although cleansing an overloaded body internally appears common sense to most people, we appreciate the need for evidence. Modern medicine does not acknowledge the validity of the ancient practice of detoxification and fasting. It is our mission to prove that the Herbal Detox should be part of our health program, and the evidence below goes a long way towards doing this.
Due to the nature of our Ultimate Herbal DETOX Program, it has been very difficult to perform clinical trials.
In the meantime, we have compiled scientific evidence and clinical trials to support the basis of our protocol.
To help form the picture, here are links to some of our other articles:
- Toxicity related health issues
- High cholesterol
- High blood pressure
- Type 2 diabetes
- Intestinal parasites
- Candida yeast infection
- Metabolic disease
- Irritable bowel syndrome
These are all conditions we have seen respond well to our Herbal DETOX program.
See Brett’s further research articles here:
Below is a series of links to evidence for the herbs in Brett’s program
These brief references are just the tip of the iceberg. Click on the names of the herbs themselves for the full research articles and Monographs.
- Blood Sugar Balance – In a pilot study, two Aloe products in patients with prediabetes over an 8-week period, tended to revert the impaired fasting glucose and impaired glucose tolerance observed in conditions of prediabetes/metabolic syndrome. (27)
- Inflammatory Bowel disease – The anti-inflammatory actions of aloe vera gel in vitro provide support for the proposal that it may have a therapeutic effect in inflammatory bowel disease. (28)
- Liver Protection – One study suggests that the protective effect of barley sprouts against alcohol-induced liver injury is potentially attributable to its inhibition of the inflammatory response induced by alcohol. (31)
- Anti-inflammatory – Barley leaf sprouts also contain a high content of the bioflavonoid saponarin, which has shown both anti-inflammatory and antioxidant activities. (31)
- Anti-parasitic – In vitro studies have suggested that plumbagin, an active constituent of Black walnut, may inhibit the motility and hatching of specific worm larvae. (19)
- Laxative – Firstly, there is stimulation of colonic motility, resulting in increased propulsion and accelerated transit of feces through the colon (which reduces fluid absorption from the fecal mass. Secondly, there is an increase in paracellular permeability across the colonic mucosa, probably due to inhibition of sodium/potassium-transporting adenosine triphosphatase or inhibition of chloride channels. (12,13)
- Ulcers – Capsaicin inhibits acid secretion, stimulates alkali and mucus secretion and particularly gastric mucosal blood flow which helps in prevention and healing of gastric ulcers. (14)
- Therapeutic effects of chia in the control of diabetes, dyslipidaemia, hypertension, as anti-inflammatory, antioxidant, anti-blood clotting, laxative, antidepressant, anti-anxiety, analgesic, vision and immune improver is scientifically established. (40)
- Heavy Metal Detox – Certain algae (Chlorella, Scenedesmus, Hydrodictyon) perform better overall than other strains. Certain algal species remove > 90% of at least one metal and their relative performance varied according to the metal being investigated. Chlorella vulgaris could tolerate a high concentration of 100 μg/ml of lead. (34)
- Heavy Metal Detox – Researchers found Cilantro (Chinese parsley) accelerates the excretion of Mercury (Hg), Lead (Pb), from the body through the urine. (32) Spirulina and Chlorella have been found to impart protection to rats exposed to lead and cadmium (33)
- Anti-bacterial – The antimicrobial activities of clove have been proved against several bacteria strains such as Escherichia coli (E. coli), Staphylococcus aureus and Bacillus cereus. (18)
- Liver protection – Results of one study suggest that the extract of Dandelion root has protective action against alcohol-induced toxicity in the liver by elevating antioxidative potentials and decreasing lipid peroxidation. (24)
- Bile flow – An extract of the whole plant increased bile secretion by 40% (25) Dandelion has been shown to favorably affect choleretic, antirheumatic and diuretic properties. (26)
- Bloating and gas – European Scientific Cooperative on Phytotherapy lists fennel seed for dyspeptic complaints such as mild, spasmodic gastrointestinal complaints, bloating, and flatulence, for catarrh of the upper respiratory tract. (7)
- Anti-spasm – A bitter fennel infusion reduced spasms (8)
- Anti-nausea – The mechanism underlying ginger’s anti-emetic activity is not clearly understood, but the aromatic, spasmolytic, carminative, and absorbent properties of ginger suggest it has direct effects on the gastrointestinal tract. (20)
- Circulation – Four clinical studies reported that ginger reduced platelet aggregation, which are responsible for blood coagulation. (21)
- Indigestion – Artichoke with multiple therapeutic properties is recommended not only in disorders of the liver, but also in the prevention of atherosclerosis and hyperlipidemia or dyspeptic disorders. (2)
- Liver protection – Artichokes multidirectional treatment is a documented fact indigestion, blood lipids and antioxidant effects. Artichoke compounds have a protective effect on liver cells. (3)
- Cholesterol – Artichoke leaf has shown cholesterol-lowering and lipid-lowering activity in rats and humans (4)
- Stomach Ulcer – Extracts of goldenseal have been shown to be very active in inhibiting Helicobacter pylori which is the major cause of stomach and peptic ulcers. (15)
- Liver stimulant – Goldenseal is a powerful bitter herb and as such can be used as a bitter liver stimulant. Recent studies show Goldenseal is a natural LDL cholesterol lowering agent with multiple bioactive components. (16)
- Anti-inflammatory – The major active constituent in Goldenseal berberine inhibits oxidative stress and inflammation in a variety of tissues including liver, adipose tissue, kidney and pancreas. (17)
- Protein digestion – In one study dietary actinidin from Kiwifruit increased gastric protein digestion and accelerated the gastric emptying for several dietary protein sources. (39)
- Antibacterial – Since the discovery of Helicobacter pylori (H. pylori) infection as the major cause of gastro-duodenal disorders including acute and chronic gastritis, gastro-duodenal ulcer, chronic atrophic gastritis, and gastric cancer almost three decades ago, the possibility of preventing these clinical diseases through eradicating H. pylori has been the focus of active research (29)
- Ulcerative Colitis – In one study 35 out of 38 Ulcerative Colitis patients taking 140mg of silymarin were in complete remission with no flare-up after 6 months. (1)
- Gastric Ulcer – The latex of the unripened fruit of papaya was effective in protecting the exogenous ulcer. The conclusion is that papain is the active principle in papaya that exerts the ulcer-protective effect. (38)
- Digestive support – Human studies on the GI, respiratory tract and analgesic effects of peppermint oil and its constituents have been reported. Several clinical trials examining the effects of peppermint oil on irritable bowel syndrome (IBS) symptoms have been conducted. (35)
- Soothing Digestion – Peppermint oil acts locally in the stomach and duodenum to produce smooth-muscle relaxation. (36)
- Diabetes – All the evidence in one comprehensive review suggest that Bromelain can be used as an effective health supplement to prevent cancer, diabetes, and various cardiovascular diseases in the long run. Bromelain may also break down cholesterol plaques. (22)
- Digestive enzyme – Bromelain aids digestion by enhancing the effects of the digestive enzymes trypsin and pepsin. It can also help to prevent heartburn by ease diarrhea, if either are caused by a deficiency of digestive enzymes. (23)
- Laxative – One study demonstrated that Psyllium husk has a gut-stimulatory effect, mediated partially by muscarinic and 5-HT(4) receptor activation, which may complement the laxative effect of its fiber content. (5)
- Cholesterol – In one study Fifty-four of 62 patients enrolled in the study completed the study Total cholesterol was significantly decreased after 3 weeks of treatment. (6)
- Irritable Bowel Syndrome – Slippery elm significantly improved both bowel habit and irritable bowel syndrome (IBS) symptoms in patients with constipation-predominant IBS (37)
- Different pharmacological experiments in a number of in vitro and in vivo models have convincingly demonstrated the abilities of rhein found in Turkish Rhubarb to exhibit hepatoprotective, nephroprotective, anti-inflammatory, antioxidant, anticancer, and antimicrobial activities, lending support to the rationale behind several of its potential medicinal uses. (30)
- Crohn’s disease – Several experimental reports suggest Artemisia absinthium is useful in the treatment of Crohn’s disease. (9) One study showed that Artemisia absinthium oil inhibited the growth of the yeast Candida albicans. (10)
- Antibacterial – Results of another study have revealed that topical application of Artemisia absinthium extract on infected wound sites produced significant antibacterial activity against Staphylococcus aureus. (11)
See my other article Scientific Research proves why we need a Herbal Detox Program
There is an overwhelming rationale for using these herbs in combination with a pure food diet to benefit long-term health.
By reducing negative gut bacteria and parasites, promoting better digestion and elimination, protecting the liver, improving bile flow, removing heavy metals, reducing blood sugar and cholesterol we can reduce and prevent the onset of the most common health problems of our time.
This must be largely due to the reduction of systemic inflammation and metabolic acidosis which would underlie many modern chronic disease states.
Our Herbal DETOX program consists of 24 herbs including all of those above. They are taken as whole herbs in capsule form in a dosage of up to 40 capsules daily. This high dose approach with a strict diet plan is probably why we have achieved such a high level of success with such a wide variety of ailments.
Brett Elliott ®
(1) A randomized, double-blinded, placebo-controlled clinical trial of silymarin in ulcerative colitis. PUBMED http://www.ncbi.nlm.nih.gov/pubmed/22528757
(2) [Artichoke–herbal drug]. PubMed http://www.ncbi.nlm.nih.gov/pubmed/23421105
(3) [Artichoke– the untapped potential of herbal medicine in the treatment of atherosclerosis and liver diseases]. [Article in Polish] Horoszkiewicz M1, Kulza M, Malinowska K, Woźniak A, Seńczuk-Przybyłowska M, Wachowiak A, Florek E. PMID: 23421107
(4) Lietti, A. 1977. Choleretic and cholesterol-lowering properties of two artichoke extracts. Fitoterapia(48):153-158.
(5) Pharmacological basis for the medicinal use of psyllium husk (Ispaghula) in constipation and diarrhea. PUBMED http://www.ncbi.nlm.nih.gov/pubmed/21082352
(6) Cholesterol reduction using psyllium husks – do gastrointestinal adverse effects limit compliance? Results of a specific observational study. PUBMED http://www.ncbi.nlm.nih.gov/pubmed/18222665
(7) ESCOP. 1997. ‘Foeniculi aetheroleum’ and ‘Foeniculi fructus.’ Monographs on the Medicinal Uses of Plant Drugs. Exeter, U.K.: European Scientific Cooperative on Phytotherapy.
(8) Nadkarni, K.M. 1976. Indian Materia Medica. Bombay: Popular Prakashan. 557559.
(9) Omer, B., Krebs, S., Omer, H., Noor, T.O., 2007. Steroid-sparing effect of wormwood (Artemisia absinthium) in Crohn’s disease: a double-blind placebo-controlled study. Phytomedicine 14, 87–95
(10) Composition and antimicrobial activity of the essential oil of Artemisia absinthium from Croatia and France. http://www.ncbi.nlm.nih.gov/pubmed/12624823
(11) Antimicrobial Activity of Artemisia absinthium Against Surgical Wounds Infected by Staphylococcus aureus in a Rat Model. http://www.ncbi.nlm.nih.gov/pubmed/24293717
(12) Bradley PR, ed. British herbal compendium. Vol. 1. Bournemouth, British Herbal Medicine Association, 1992.
(13) De Witte P. Metabolism and pharmacokinetics of the anthranoids. Pharmacology 1993, 47 (Suppl. 1):86–97.
(14) Biological Activities of Red Pepper (Capsicum annuum) and Its Pungent Principle Capsaicin: A Review. http://www.ncbi.nlm.nih.gov/pubmed/25675368
(15) In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastiscanadensis. PubMed http://www.ncbi.nlm.nih.gov/pubmed/12672149 Investigations into the antibacterial activities of phytotherapeutics against Helicobacter pylori and Campylobacter jejuni. PubMed http://www.ncbi.nlm.nih.gov/pubmed/?term=golden+seal+ulcer
(16) The medicinal plant goldenseal is a natural LDL-lowering agent with multiple bioactive components and new action mechanisms. PubMed http://www.ncbi.nlm.nih.gov/pubmed/16885565
(17) Antioxidant and anti-inflammatory activities of berberine in the treatment of diabetes mellitus. PubMed http://www.ncbi.nlm.nih.gov/pubmed/24669227
(18) Clove (Syzygium aromaticum): a precious spice PubMed http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819475/
(19) Fetterer, R., Fleming, MW., Comp Biochem Physiol C, 1991. 100(3): p. 539-342. Effects of plumbagin on development of the parasitic nematodes Haemonchus contortus and Ascaris suum PubMed http://www.ncbi.nlm.nih.gov/pubmed/?term=1687553
(20) Tyler VE. Some recent advances in herbal medicine. Pharm Int 1986;7:203-207. http://www.altmedrev.com/publications/8/3/331.pdf
(21) The Effect of Ginger (Zingiber officinale) on Platelet Aggregation: A Systematic Literature Review. PubMed http://www.ncbi.nlm.nih.gov/pubmed/26488162
(22) Properties and Therapeutic Application of Bromelain: A Review PubMed http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529416/
(23) Exogenous proteases for meat tenderization. PubMed http://www.ncbi.nlm.nih.gov/pubmed/24499119
(24) In vitro and in vivo hepatoprotective effects of the aqueous extract from Taraxacum officinale (dandelion) root against alcohol-induced oxidative stress. PubMed http://www.ncbi.nlm.nih.gov/pubmed/20347918
(25) World Health Organization. Medicinal Plants http://apps.who.int/medicinedocs/documents/s17534en/s17534en.pdf
(26) Hypolipidemic and antioxidant effects of dandelion (Taraxacum officinale) root and leaf on cholesterol-fed rabbits. PubMed http://www.ncbi.nlm.nih.gov/pubmed/20162002
(27) Evaluation of biological properties and clinical effectiveness of Aloe vera: A systematic review. PUBMED http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488101/
(28) Anti-inflammatory effects of aloe vera gel in human colorectal mucosa in vitro. PUBMED: http://www.ncbi.nlm.nih.gov/pubmed/14987320
(29) Dietary, non-microbial intervention to prevent Helicobacter pylori-associated gastric diseases. PUBMED https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481371/
(30) Rhein: A Review of Pharmacological Activities. PUBMED https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491579/
(31) Barley Sprouts Extract Attenuates Alcoholic Fatty Liver Injury in Mice by Reducing Inflammatory Response. PUBMED https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963916/
(32) Role of mercury (Hg) in resistant infections & effective treatment of Chlamydia trachomatis and Herpes family viral infections (and potential treatment for cancer) by removing localized Hg deposits with Chinese parsley and delivering effective antibiotics using various drug uptake enhancement methods. PUBMED http://www.ncbi.nlm.nih.gov/pubmed/8686573/
(33) Phytochemicals Mediated Remediation of Neurotoxicity Induced by Heavy Metals. PUBMED http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4651672/
(34) The bioremoval capacity of three heavy metals by some microalgae species (Egyptian Isolates). PUBMED http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3443921/
(35) A review of the bioactivity and potential health benefits of peppermint tea (Mentha piperita L.). PUBMED https://www.ncbi.nlm.nih.gov/pubmed/16767798
(36) Botanical perspectives on health peppermint: more than just an after-dinner mint. PUBMED https://www.ncbi.nlm.nih.gov/pubmed/11329700
(37) Effects of two natural medicine formulations on irritable bowel syndrome symptoms: a pilot study. PUBMED http://www.ncbi.nlm.nih.gov/pubmed/20954962
(38) Protective effects of Carica papaya Linn on the exogenous gastric ulcer in rats. PUBMED https://www.ncbi.nlm.nih.gov/pubmed/7053020
(39) Dietary actinidin from kiwifruit (Actinidia deliciosa cv. Hayward) increases gastric digestion and the gastric emptying rate of several dietary proteins in growing rats. PUBMED https://www.ncbi.nlm.nih.gov/pubmed/24431326
(40) Nutritional and therapeutic perspectives of Chia (Salvia hispanica L.): a review. PUBMED https://www.ncbi.nlm.nih.gov/pubmed/27413203